Comparative analysis of the biotechnological potential of Knautia drymeia Heuff. and K. macedonica Griseb

The present study of Knautia drymeia and K. macedonica is in line with the current trend searching for new plant species that can potentially be used as medicinal herb materials. A comparative analysis morphological anatomical structure both was performed together distribution polyphenolic compounds, which correlated tissue organs. Quantitative phytochemical analyses were to supplement biophysical analyses. Both had a similar morphological, anatomical, histological structure. Polyphenolic compounds accumulated parenchyma an organ-specific mode, mainly leaves. revealed organ- species-dependent variations polyphenol content. Thus, highest amount observed leaves, equal levels total polyphenols phenolic acids leaves drymeia, respectively. integrates morphological/histological investigations biotechnological/pharmaceutical potential studied plants constitutes innovative holistic approach research problem.